Phospho-RAD9(S277) polyclonal, anti-human
€0.00
In stock
SKU
AC-AP3224a
Catalog Number: AC-AP3224a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7111
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7111
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Rad9 is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade.
Other Names:
Cell cycle checkpoint control protein RAD9A, hRAD9, DNA repair exonuclease rad9 homolog A, RAD9A
Target/Specificity:
This RAD9 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S277 of human RAD9.
Antigen Type: Synthetic Peptide
Gene Name: RAD9A
Gene ID: 5883
Primary Accession: Q99638
NCBI Accession: NP_001230153.1;NP_004575.1
Other Accession: Q4R5X9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Rad9 is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade.
Other Names:
Cell cycle checkpoint control protein RAD9A, hRAD9, DNA repair exonuclease rad9 homolog A, RAD9A
Target/Specificity:
This RAD9 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S277 of human RAD9.
Antigen Type: Synthetic Peptide
Gene Name: RAD9A
Gene ID: 5883
Primary Accession: Q99638
NCBI Accession: NP_001230153.1;NP_004575.1
Other Accession: Q4R5X9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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