Phospho-rat TSC1(T417) polyclonal, anti-rat

Phospho-rat TSC1(T417) polyclonal, anti-rat

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In stock
SKU
AC-AP3831a
Catalog Number: AC-AP3831a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41269
Applications: DB
Datasheet

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Background:
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).

Other Names:
Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1

Target/Specificity:
This rat TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T417 of rat TSC1.

Antigen Type: Synthetic Peptide

Gene Name: Tsc1 {ECO:0000303|PubMed:10029074, ECO:0000312|RGD:620124}
Gene ID: 60445
Primary Accession: Q9Z136
NCBI Accession: NP_068626.1
Other Accession: NP_068626.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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