Phospho-rat TSC1(Y297) Blocking Peptide
€363.00
In stock
SKU
AC-BP3832a
Background:
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Other Names:
Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1
Target/Specificity:
The synthetic peptide sequence is selected from aa 291-304 of RAT Tsc1
Gene Name: Tsc1 {ECO:0000303|PubMed:10029074, ECO:0000312|RGD:620124}
Gene ID: 60445
Primary Accession: Q9Z136
Other Accession: NP_068626.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Other Names:
Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1
Target/Specificity:
The synthetic peptide sequence is selected from aa 291-304 of RAT Tsc1
Gene Name: Tsc1 {ECO:0000303|PubMed:10029074, ECO:0000312|RGD:620124}
Gene ID: 60445
Primary Accession: Q9Z136
Other Accession: NP_068626.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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