Phospho-SLAMF1(Y307) Antibody Blocking peptide
€363.00
In stock
SKU
AC-BP3673a
Background:
SLAMF1 is high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
Other Names:
Signaling lymphocytic activation molecule, CDw150, IPO-3, CD150, SLAMF1, SLAM
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3673a was selected from the region of human Phospho-SLAMF1-pY307. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SLAMF1
Gene ID: 6504
Primary Accession: Q13291
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
SLAMF1 is high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
Other Names:
Signaling lymphocytic activation molecule, CDw150, IPO-3, CD150, SLAMF1, SLAM
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3673a was selected from the region of human Phospho-SLAMF1-pY307. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SLAMF1
Gene ID: 6504
Primary Accession: Q13291
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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