Phospho-SMAD3(T179) Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction, Stem Cells

Synonyms:
HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3, SMAD3

Immunogen: A synthetic phosphorylated peptide around T179 of human SMAD3 (NP_005893.1).

Swissprot: P84022
Gene ID: 4088

Calculated MW: 25 kDa/35 kDa/43 kDa/48 kDa
Observed MW: 48 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "
WB 1:500-1:2000
IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.