Phospho-SRC(Y215) polyclonal, anti-human
€0.00
In stock
SKU
AC-AP3253a
Catalog Number: AC-AP3253a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB8173
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB8173
Applications: WB
Datasheet
Request Information
Background:
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. Transcript Variant: This variant (1) represents the longer transcript. Both isoforms 1 and 2 encode the same protein.
Other Names:
Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src, SRC, SRC1
Target/Specificity:
This SRC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y215 of human SRC.
Antigen Type: Synthetic Peptide
Gene Name: SRC (HGNC:11283)
Gene ID: 6714
Primary Accession: P12931
NCBI Accession: NP_005408.1;NP_938033.1
Other Accession: Q9WUD9; P05480; Q1JPZ3; P00523; P13116; P13115
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. Transcript Variant: This variant (1) represents the longer transcript. Both isoforms 1 and 2 encode the same protein.
Other Names:
Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src, SRC, SRC1
Target/Specificity:
This SRC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y215 of human SRC.
Antigen Type: Synthetic Peptide
Gene Name: SRC (HGNC:11283)
Gene ID: 6714
Primary Accession: P12931
NCBI Accession: NP_005408.1;NP_938033.1
Other Accession: Q9WUD9; P05480; Q1JPZ3; P00523; P13116; P13115
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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