Phospho-SRC(Y529) Polyclonal Antibody

Background:
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
ASV, SRC1, THC6, c-SRC, p60-Src, SRC

Immunogen: A synthetic phosphorylated peptide around Y529 of human SRC (NP_005408.1).

Swissprot: P12931
Gene ID: 6714

Calculated MW: 59 kDa/60 kDa
Observed MW: 60 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.