Phospho-STAT2 (Tyr690) Polyclonal Antibody

Background:
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STA

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
Homo sapiens interferon alpha induced transcriptional activator, interferon alpha induced transcriptional activator, ISGF 3, ISGF3, MGC59816, P113, signal transducer and activator of transcription 2 113kD, Signal transducer and activator of transcription 2, STAT113, Stat2, STAT2

Immunogen: Synthesized peptide derived from human Stat2 around the phosphorylation site of Tyr690

Swissprot: P52630

Calculated MW: 98 kDa
Observed MW: 113 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.