Phospho-STAT4-Y693 Antibody Blocking Peptide

Background:
STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT4 is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.

Other Names:
Signal transducer and activator of transcription 4, STAT4

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3264a was selected from the region of human Phospho-STAT4-Y693. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: STAT4

Gene ID: 6775
Primary Accession: Q14765
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.