Phospho-Tau(S396) Polyclonal Antibody

Background:
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, MAPT, Tau

Immunogen: A phospho specific peptide corresponding to residues surrounding S396 of human Tau

Swissprot: P10636
Gene ID: 4137

Calculated MW: 32-45 kDa/78- 80 kDa
Observed MW: 50 kDa/60 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.