Phospho-TrkA polyclonal, anti-human, mouse, rat antibody
€375.00
In stock
SKU
AC-ABV10372-100
Catalog Number: AC-ABV10372-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IF, IP
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IF, IP
Datasheet
Request Information
Background:
TrkA, the high affinity Nerve Growth Factor (NGF) receptor, autophosphorylates on tyrosine to activate multiple effectors. Phosphorylation at Tyr490 is required for Shc association and activation of the Ras-MAP kinase cascade. Residues Tyr674/675 lie within the catalytic domain, and phosphorylation at these sites reflects Trk kinase activity.
Other Names:
TRK , TRKA , Trk-A , MTC , CIPA , NTRK1 , MTC , TRK1 , p140-TrkA , DKFZp781I14186
Primary Accession: P04629
Other Accession: BAA34355
Gene Name: NTRK1
Gene ID: 4914
Concentration (mg/ml): 0.5 mg/ml
TrkA, the high affinity Nerve Growth Factor (NGF) receptor, autophosphorylates on tyrosine to activate multiple effectors. Phosphorylation at Tyr490 is required for Shc association and activation of the Ras-MAP kinase cascade. Residues Tyr674/675 lie within the catalytic domain, and phosphorylation at these sites reflects Trk kinase activity.
Other Names:
TRK , TRKA , Trk-A , MTC , CIPA , NTRK1 , MTC , TRK1 , p140-TrkA , DKFZp781I14186
Primary Accession: P04629
Other Accession: BAA34355
Gene Name: NTRK1
Gene ID: 4914
Concentration (mg/ml): 0.5 mg/ml
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