Phospho-YAP1(S127) Polyclonal Antibody

Background:
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
COB1, YAP, YAP2, YAP65, YKI, YAP1

Immunogen: A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1).

Swissprot: P46937
Gene ID: 10413

Calculated MW: 36 kDa/48 kDa/49 kDa/50 kDa/52 kDa/53 kDa/54 kDa
Observed MW: 60 kDa/68 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:1000 IF 1:20-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.