Phospho-YWHAE(T232) Antibody Blocking peptide
€363.00
In stock
SKU
AC-BP3001a
Background:
The 14-3-3 family of proteins mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer.
Other Names:
14-3-3 protein epsilon, 14-3-3E, YWHAE
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3001a was selected from the region of human Phospho-14-3-3-T232. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: YWHAE
Gene ID: 7531
Primary Accession: P62258
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The 14-3-3 family of proteins mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer.
Other Names:
14-3-3 protein epsilon, 14-3-3E, YWHAE
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3001a was selected from the region of human Phospho-14-3-3-T232. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: YWHAE
Gene ID: 7531
Primary Accession: P62258
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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