Phosphodiesterase 4B polyclonal, anti-mouse

Background:
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Other Names:
cAMP-specific 3',5'-cyclic phosphodiesterase 4B, 3.1.4.53, DPDE4, PDE32, PDE4B, DPDE4

Antigen Types:
Synthetic Peptide

Gene Name:
PDE4B (HGNC:8781)
Gene ID:
5142
Primary Accession: Q07343
Other Accession: NP_001032417;5142;