Phosphotyrosine [clone PY20], anti-all species

Description: Protein phosphorylation is a fundamental event in the regulation of a large number of intracellular processes. Phosphorylation of specific tyrosine residues is the result of activation or stimulation of their respective protein tyrosine kinases. The phosphorylated proteins can be auto-phosphorylated kinases or certain cellular protein substrates. Tyrosine-phosphorylated proteins are involved in signal transduction and in the regulation of cell proliferation. An antibody to phosphotyrosine provides an excellent tool for the detection, characterization, and purification of phosphotyrosine-containing proteins.Localization: Depends upon the location of phosphorylated targetDilution: 50-200Positive Control: breast ca MCF-7, MDA-231, T47-D cellsHIER: noneStatus: RUO