Phosphotyrosine polyclonal, anti-human, mouse, rat

Protein Family: Protein Kinases

Pathway and Disease: Signaling Molecules and Interaction, Signal Transduction

Description:
Tyrosine is one of the 20 naturally occurring amino acids used for the biosynthesis of proteins. Kinases phosphorylate tyrosine to phosphotyrosine which is considered as a key step in the regulation of enzymatic activities such as signal transduction. This antibody recognizes proteins and peptides phosphorylated on tyrosine residues. There is no cross-reactivity with phosphoserine and phosphothreonine.

Alternate Names: Phosphotyrosine, pY, Phospho-tyrosine, pTyr, Phospho-Tyr, Phosphotyr

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:50-1:100; IP: 1:50-1:100

Antigen: KLH-conjugated iodoacetylphosphotyramine

Format: Each vial contains 0.1 mg IgG in 0.4 ml (0.25 mg/ml) of PBS pH7.0 with 0.01% sodium azide. Antibody was purified by immunogen-affinity chromatography using phosphotyrosine coupled to agarose.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.