PHOX2B polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71323
Background:
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element.
Alternative Name:
PMX2B, NBLST2, NBPhox
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: PHOX2B polyclonal antibody detects endogenous levels of PHOX2B protein.
Immunogen:
Recombinant protein of human PHOX2B.
MW: ~ 32 kDa
Swis Prot.: Q99453
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element.
Alternative Name:
PMX2B, NBLST2, NBPhox
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: PHOX2B polyclonal antibody detects endogenous levels of PHOX2B protein.
Immunogen:
Recombinant protein of human PHOX2B.
MW: ~ 32 kDa
Swis Prot.: Q99453
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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