PHOX2B polyclonal (Center), anti-mouse

PHOX2B polyclonal (Center), anti-mouse

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In stock
SKU
AC-AP11341C
Catalog Number: AC-AP11341C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28842
Applications: WB, IF
Datasheet

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Background:
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq].

Other Names:
Paired mesoderm homeobox protein 2B, Neuroblastoma Phox, NBPhox, PHOX2B homeodomain protein, Paired-like homeobox 2B, PHOX2B, PMX2B

Target/Specificity:
This PHOX2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-130 amino acids from the Central region of human PHOX2B.

Antigen Region:
104-130

Antigen Type: Synthetic Peptide

Gene Name: PHOX2B
Gene ID: 8929
Primary Accession: Q99453
NCBI Accession: NP_003915.2
Other Accession: O35690; Q62782; Q62066; O14813; NP_003915.2; G5EC89
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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