PI 3 kinase p85 alpha Monoclonal Antibody

Background:
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.

Research Area: Cancer, Metabolism, Immunology, Signal Transduction

Synonyms:
GRB1, p85 alpha, p85, P85A, Phosphatidylinositol 3 kinase associated p 85 alpha, Phosphatidylinositol 3 kinase regulatory 1, Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 1 (p85 alpha), Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphoinositide 3 kinase, regulatory subunit 1 (alpha), PI3 kinase p85 subunit alpha, PI3-kinase regulatory subunit alpha, PI3-kinase subunit p85-alpha, PI3K, PI3K regulatory subunit alpha, Pik3r1, PtdIns 3 kinase p85 alpha, PtdIns-3-kinase regulatory subunit alpha, PtdIns-3-kinase regulatory subunit p85-alpha

Immunogen: Recombinant Protein

Swissprot: P27986
Observed MW: 85 kDa

Purification Method: Protein A purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:1000-2000, IHC 1:100-200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.