PI 3-Kinase p85β rabbit polyclonal, anti-human, mouse, rat

Backgroud: Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2012],function:Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.,similarity:Belongs to the PI3K p85 subunit family.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 SH2 domains.,subunit:Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunits.,

Synonyms: p85, p85 beta, p85-BETA, P85B, P85B_HUMAN, Phosphatidylinositol 3 kinase, Phosphatidylinositol 3 kinase regulatory beta subunit, Phosphatidylinositol 3 kinase regulatory subunit beta, Phosphatidylinositol 3 kinase regulatory subunit polypeptide 2, Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 2 (p85 beta), Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, phosphatidylinositol 3-kinase, Phosphatidylinositol 3-kinase regulatory beta subunit, Phosphatidylinositol 3-kinase regulatory subunit beta, Phosphoinositide 3 kinase regulatory subunit 2 (beta), Phosphoinositide 3 kinase regulatory subunit 2, Phosphoinositide 3 kinase regulatory subunit polypeptide 2 (p85 beta), Phosphoinositide 3 kinase regulatory subunit polypeptide 2, Phosphoinositide 3 kinase, regulatory subunit 2 (beta), Phosphoinositide 3 kinase, regulatory subunit 2 (p85 beta), PI3 kinase p85 beta subunit, PI3 kinase p85 subunit beta, PI3-kinase regulatory subunit beta, PI3-kinase subunit p85-beta, PI3K, PI3K regulatory subunit beta, PIK3R 2, PIK3R2, polypeptide 2 (p85 beta), PtdIns 3 kinase p85 beta, PtdIns-3-kinase p85-beta, PtdIns-3-kinase regulatory subunit beta, PtdIns-3-kinase regulatory subunit p85-beta.

Gene Name: PIK3R2

Gene ID: 5296

SwissProt ID: O00459

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.