PI3 Kinase p85 alpha Polyclonal Antibody

Background:
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.

Research Area: Cancer, Metabolism, Immunology, Signal Transduction

Synonyms:
AGM7, GRB1, IMD36, p85, p85-ALPHA, PI3 Kinase p85 alpha, PIK3R1

Immunogen: Recombinant fusion protein of human PI3 Kinase p85 alpha (NP_852556.2).

Swissprot: P27986
Gene ID: 5295

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.