PI3 Polyclonal Antibody

Background:
This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.

Research Area: Cancer, Cell Biology, Immunology, Microbiology

Synonyms:
PI3, ESI, SKALP, WAP3, WFDC14, cementoin, elafin

Immunogen: Recombinant fusion protein of human PI3 (NP_002629.1).

Swissprot: P19957
Gene ID: 5266

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.