IQGAP1 polyclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP70570
Background:
Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth (PubMed:15695813). May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest (PubMed:20883816).
Other Names:
IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195
Antigen Type: synthetic peptide
Antigen Type: IQGAP1
Gene ID: 8826
Primary Accession: P46940
Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth (PubMed:15695813). May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest (PubMed:20883816).
Other Names:
IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195
Antigen Type: synthetic peptide
Antigen Type: IQGAP1
Gene ID: 8826
Primary Accession: P46940
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