PI4KCB polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP8030a
Catalog Number: AC-AP8030a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1676
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1676
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Phosphoinositides are pivotal precursors to important second messengers and as signaling and molecules. Phosphatidylinositol 4-kinases (PI4Ks) are are crucial regulators of the phosphoinsitide cascade. PI4KCB is a wortmannin-sensitive PI 4-kinase responsible for regulating the synthesis of agonist-sensitive pools of polyphosphoinositides. The cellular reservoir of PI4KCB is predominantly cytosolic, however the protein is is activated strongly by recruitment to the membrane to stimulate phosphatidylinositol 4,5-bisphosphate synthesis at the plasma membrane. PI4KCB contains an N-terminal lipid kinase unique domain, which is shared by members of both the PI3 kinase and PI4 kinase families, and a C-terminal catalytic domain, which defines this protein as a member of a much larger protein/lipid kinase family.
Other Names:
Phosphatidylinositol 4-kinase beta, PI4K-beta, PI4Kbeta, PtdIns 4-kinase beta, NPIK, PI4K92, PI4KB, PIK4CB
Target/Specificity:
This PI4KCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-51 amino acids from the N-terminal region of human PI4KCB.
Antigen Region:
20-51
Antigen Type: Synthetic Peptide
Gene Name: PI4KB (HGNC:8984)
Gene ID: 5298
Primary Accession: Q9UBF8
NCBI Accession: NP_001185702.1;NP_001185703.1;NP_001185704.1;NP_002642.1
Other Accession: O08561; Q8BKC8; O02810; Q5VWB9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Phosphoinositides are pivotal precursors to important second messengers and as signaling and molecules. Phosphatidylinositol 4-kinases (PI4Ks) are are crucial regulators of the phosphoinsitide cascade. PI4KCB is a wortmannin-sensitive PI 4-kinase responsible for regulating the synthesis of agonist-sensitive pools of polyphosphoinositides. The cellular reservoir of PI4KCB is predominantly cytosolic, however the protein is is activated strongly by recruitment to the membrane to stimulate phosphatidylinositol 4,5-bisphosphate synthesis at the plasma membrane. PI4KCB contains an N-terminal lipid kinase unique domain, which is shared by members of both the PI3 kinase and PI4 kinase families, and a C-terminal catalytic domain, which defines this protein as a member of a much larger protein/lipid kinase family.
Other Names:
Phosphatidylinositol 4-kinase beta, PI4K-beta, PI4Kbeta, PtdIns 4-kinase beta, NPIK, PI4K92, PI4KB, PIK4CB
Target/Specificity:
This PI4KCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-51 amino acids from the N-terminal region of human PI4KCB.
Antigen Region:
20-51
Antigen Type: Synthetic Peptide
Gene Name: PI4KB (HGNC:8984)
Gene ID: 5298
Primary Accession: Q9UBF8
NCBI Accession: NP_001185702.1;NP_001185703.1;NP_001185704.1;NP_002642.1
Other Accession: O08561; Q8BKC8; O02810; Q5VWB9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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