PIAS1 polyclonal, anti-human

Background:
This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. 

Synonyms: GBP, ZMIZ3, DDXBP1, GU/RH-II

Cellular Location: Nucleus Nucleus speckle PML body

Immunogen:
A synthetic peptide of human PIAS1

Gene Symbol: PIAS1

Gene ID: 8554

Swiss prot: O75925

Calculated MW: 72 kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.