PIAS1 polyclonal, anti-human, mouse

Background:
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.

Synonyms: DDXBP1, GBP, GU/RH-II, ZMIZ3

Cellular Location: Nucleus Nucleus speckle PML body

Immunogen:
Recombinant protein of human PIAS1

Gene Symbol: PIAS1

Gene ID: 8554

Swiss prot: O75925

Calculated MW: 72kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.