PIAS1 Polyclonal Antibody

Background:
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
PIAS1, DDXBP1, GBP, GU/RH-II, ZMIZ3

Immunogen: Recombinant fusion protein of human PIAS1 (NP_057250.1).

Swissprot: O75925
Gene ID: 8554

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.