PIAS3 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.

Synonyms: ZMIZ5

Cellular Location: Cytoplasm Nucleus

Immunogen:
A synthetic peptide of human PIAS3

Gene Symbol: PIAS3

Gene ID: 10401

Swiss prot: Q9Y6X2

Calculated MW: 68kDa

Recommended dilution:
IHC 1:40-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.