PIAS3 Polyclonal Antibody

Background:
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
E3 SUMO protein ligase PIAS 3, E3 SUMO protein ligase PIAS3, E3 SUMO-protein ligase PIAS3, FLJ14651, OTTHUMP00000015586, OTTHUMP00000015587, PIAS 3, Pias3, PIAS3 protein, PIAS3, Protein inhibitor of activated STAT 3, Protein inhibitor of activated STAT protein 3, Protein inhibitor of activated STAT3, Zinc finger MIZ type containing 5, ZMIZ 5, ZMIZ5

Immunogen: Synthetic peptide of human PIAS3

Swissprot: Q9Y6X2
Gene Accession: NP006090

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.1 mg/mL
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.