PIAS3 Polyclonal Antibody

Background:
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
PIAS3, ZMIZ5

Immunogen: Recombinant fusion protein of human PIAS3 (NP_006090.2).

Swissprot: Q9Y6X2
Gene ID: 10401

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.