PIAS4 polyclonal (N-term), anti-mouse
€0.00
In stock
SKU
AC-AP14013a
Catalog Number: AC-AP14013a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33956
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33956
Applications: WB
Datasheet
Request Information
Background:
PIAS4 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Promotes PARK7 sumoylation. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations.
Other Names:
E3 SUMO-protein ligase PIAS4, 632-, PIASy, Protein inhibitor of activated STAT protein 4, Protein inhibitor of activated STAT protein gamma, PIAS-gamma, PIAS4, PIASG
Target/Specificity:
This PIAS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human PIAS4.
Antigen Region:
44-73
Antigen Type: Synthetic Peptide
Gene Name: PIAS4 {ECO:0000303|PubMed:32832608, ECO:0000312|HGNC:HGNC:17002}
Gene ID: 51588
Primary Accession: Q8N2W9
NCBI Accession: NP_056981.2
Other Accession: NP_056981.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
PIAS4 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Promotes PARK7 sumoylation. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations.
Other Names:
E3 SUMO-protein ligase PIAS4, 632-, PIASy, Protein inhibitor of activated STAT protein 4, Protein inhibitor of activated STAT protein gamma, PIAS-gamma, PIAS4, PIASG
Target/Specificity:
This PIAS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human PIAS4.
Antigen Region:
44-73
Antigen Type: Synthetic Peptide
Gene Name: PIAS4 {ECO:0000303|PubMed:32832608, ECO:0000312|HGNC:HGNC:17002}
Gene ID: 51588
Primary Accession: Q8N2W9
NCBI Accession: NP_056981.2
Other Accession: NP_056981.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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