PICK1 polyclonal, anti-human

Background:
The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.

Synonyms: PICK, PRKCABP

Cellular Location: Cell junction Cytoplasm Lipid-anchor Membrane Peripheral membrane protein cytoskeleton perinuclear region postsynaptic cell membrane postsynaptic density synapse synaptosome

Immunogen:
A synthetic peptide of human PICK1

Gene Symbol: PICK1

Gene ID: 9463

Swiss prot: Q9NRD5

Calculated MW: 47kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.