PIGA polyclonal (C-term), anti-human
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In stock
SKU
AC-AP12378b
Catalog Number: AC-AP12378b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31291
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31291
Applications: IHC-P, WB
Datasheet
Request Information
Background:
This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12.
Other Names:
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A, GlcNAc-PI synthesis protein, Phosphatidylinositol-glycan biosynthesis class A protein, PIG-A, PIGA
Target/Specificity:
This PIGA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 455-484 amino acids from the C-terminal region of human PIGA.
Antigen Region:
455-484
Antigen Type: Synthetic Peptide
Gene Name: PIGA (HGNC:8957)
Gene ID: 5277
Primary Accession: P37287
NCBI Accession: NP_002632.1;NP_065206.3
Other Accession: NP_065206.3;NP_002632.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12.
Other Names:
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A, GlcNAc-PI synthesis protein, Phosphatidylinositol-glycan biosynthesis class A protein, PIG-A, PIGA
Target/Specificity:
This PIGA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 455-484 amino acids from the C-terminal region of human PIGA.
Antigen Region:
455-484
Antigen Type: Synthetic Peptide
Gene Name: PIGA (HGNC:8957)
Gene ID: 5277
Primary Accession: P37287
NCBI Accession: NP_002632.1;NP_065206.3
Other Accession: NP_065206.3;NP_002632.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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