PIK3C3 Polyclonal Antibody

Background:
Phosphatidylinositol 3-kinase catalytic subunit type 3is anenzymethat in humans is encoded by thePIK3C3gene. PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation.

Research Area: Cancer, Metabolism, Immunology, Signal Transduction

Synonyms:
PIK3C3, VPS34, Vps34, hVps34

Immunogen: A synthetic peptide of human PIK3C3

Swissprot: Q8NEB9
Gene ID: 5289

Calculated MW: 101 kDa
Observed MW: 100 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:200-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.