PIK3CA Polyclonal Antibody

Background:
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4, 5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.

Research Area: Cancer, Immunology, Signal Transduction

Synonyms:
PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, PI3K-alpha

Immunogen: A synthetic peptide of human PIK3CA

Swissprot: P42336
Gene ID: 5290

Calculated MW: 124 kDa
Observed MW: 110 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.