PIK3CG (clone 4B5D2), anti-human
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In stock
SKU
BT-MCA2442
Catalog Number: BT-MCA2442
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s):
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s):
Datasheet
Request Information
Background:
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.
Research Area: Signal Transduction
Synonyms: PI3K, PIK3, PI3CG, PI3Kgamma, p110gamma, p120-PI3K
Immunogen: Purified recombinant fragment of human PIK3CG (AA: 1-100) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
Storage:
4°C|-20°C for long term storage
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.
Research Area: Signal Transduction
Synonyms: PI3K, PIK3, PI3CG, PI3Kgamma, p110gamma, p120-PI3K
Immunogen: Purified recombinant fragment of human PIK3CG (AA: 1-100) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
Storage:
4°C|-20°C for long term storage
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