PIK3CG Polyclonal Antibody

Background:
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.

Research Area: Cancer, Immunology, Signal transduction

Synonyms:
1 phosphatidylinositol 3 kinase, 5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma, 5-bisphosphate 3-kinase catalytic subunit gamma isoform, p110 gamma, p110gamma, p120 PI3K, p120-PI3K, Phosphatidylinositol 3 kinase catalytic 110 kD gamma, Phosphatidylinositol 3 kinase gamma, p110 gamma, Phosphatidylinositol 3 kinase, catalytic, gamma polypeptide, Phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit gamma, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit gamma, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit gamma isoform, Phosphatidylinositol-4, Phosphoinositide 3 kinase catalytic gamma polypeptide, Phosphoinositide 3 kinase gamma catalytic subunit, PI3 kinase p110 subunit gamma, PI3-kinase subunit gamma, PI3CG, PI3K, PI3K-gamma, PI3Kgamma, PIK3, Pik3cg, PK3CG, PtdIns-3-kinase subunit gamma, PtdIns-3-kinase subunit p110-gamma, Serine/threonine protein kinase PIK3CG

Immunogen: Synthetic peptide of human PIK3CG

Swissprot: P48736
Gene Accession: NP_002640

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1405/sc-1404/sc-7177