PIK3R1 polyclonal, anti-mouse, rat

Background:
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.

Synonyms: AGM7, GRB1, IMD36, p85, p85-ALPHA

Cellular Location: Cytosol Endoplasmic reticulum Golgi apparatus Nucleus Plasma Membrane

Immunogen:
Recombinant protein of human PIK3R1

Gene Symbol: PIK3R1

Gene ID: 5295

Swiss prot: P27986

Calculated MW: 84kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.