PIK3R3 polyclonal (C-term), anti-human

PIK3R3 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP8025a
Catalog Number: AC-AP8025a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1719
Applications: IF, WB, IHC-P
Datasheet

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Background:
PIK3R3 binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. It is a component of a heterodimer of p110 (catalytic) and p55 (regulatory) subunits. The protein is expressed at highest levels in brain and testis. Lower levels are detected in adipose tissue, kidney, heart, lung and skeletal muscle. The protein contains 2 SH2 domains.

Other Names:
Phosphatidylinositol 3-kinase regulatory subunit gamma, PI3-kinase regulatory subunit gamma, PI3K regulatory subunit gamma, PtdIns-3-kinase regulatory subunit gamma, Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma, PI3-kinase subunit p55-gamma, PtdIns-3-kinase regulatory subunit p55-gamma, p55PIK, PIK3R3

Target/Specificity:
This PIK3R3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-346 amino acids from the C-terminal region of human PIK3R3.

Antigen Region:
316-346

Antigen Type: Synthetic Peptide

Gene Name: PIK3R3
Gene ID: 8503
Primary Accession: Q92569
NCBI Accession: NP_001107644.1;NP_003620.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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