LMTK3 polyclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP70759
Background:
Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl- D-aspartate receptors (NMDAR) in neurons (By similarity).
Other Names:
LMTK3; KIAA1883; TYKLM3; Serine/threonine-protein kinase LMTK3; Lemur tyrosine kinase 3
Antigen Type: synthetic peptide
Antigen Type: LMTK3
Primary Accession: Q96Q04
Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl- D-aspartate receptors (NMDAR) in neurons (By similarity).
Other Names:
LMTK3; KIAA1883; TYKLM3; Serine/threonine-protein kinase LMTK3; Lemur tyrosine kinase 3
Antigen Type: synthetic peptide
Antigen Type: LMTK3
Primary Accession: Q96Q04
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