PIKFYVE Polyclonal Antibody

Background:
Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
1 phosphatidylinositol 3 phosphate 5 kinase, 1 phosphatidylinositol 4 phosphate 5 kinase, 1-phosphatidylinositol 3-phosphate 5-kinase, CFD, epididymis luminal protein 37, FAB1, FAB1, S. cerevisiae, homolog of, FYV1, FYVE finger containing phosphoinositide kinase, FYVE finger-containing phosphoinositide kinase, KIAA0981, MGC40423, p235, Phosphatidylinositol 3 phosphate 5 kinase type III, Phosphatidylinositol 3 phosphate/phosphatidylinositol 5 kinase type III, Phosphatidylinositol 3-phosphate 5-kinase, Phosphatidylinositol 3-phosphate 5-kinase type III, Phosphatidylinositol 4 phosphate 5 kinase type III, Phosphoinositide kinase, FYVE finger containing, PIKfyve, PIP5K, PIP5K3, PIPkin III, PIPkin-III, PtdIns(4)P 5 kinase, Type III PIP kinase, ZFYVE29, Zinc finger, FYVE domain containing 29

Immunogen: Recombinant protein of human PIKFYV

Swissprot: Q9Y2I7
Gene Accession: BC032389

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.