PIM1 Peptide

PIM1 Peptide

€100.00
In stock
SKU
350482
Catalog Number: 350482
Size: 0.1 mg
Datasheet
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Protein Family: Enzymes, Peptidases, Protein Kinases

Pathway and Disease: Cancers, Signal Transduction

Alternate Names: Proto-oncogene serine/threonine-protein kinase pim-1

Accession No.: P11309, Q5T7H7, NP_002639

Description:
PIM1, a CAMK Ser/Thr protein kinase, plays a role in signal transduction in blood cells. PIM1 contributes to both cell proliferation and survival, providing a selective advantage in tumerogenesis. PIM1 is strongly induced in leukocytes by the JAK/STAT pathway in response to cytokines.

Format:
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

MW: 2046.3 g/mol

Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200120 is selected from a sequence within the C-term region of human PIM1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Composition:
C89H144N24O29S1

Purity:
> 80% by HPLC

Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
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