PIN1 antibody (clone 2F2), anti-human
€435.00
In stock
SKU
AC-AT3312a
Catalog Number: AC-AT3312a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB
Request Information AC-AT3312a">Request Information
Background:
Peptidyl-prolyl cis/trans isomerases (PPIases; EC 5.2.1.8), such as PIN1, catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. PIN1 is the only PPIase that specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. PIN1-catalyzed conformational regulation has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, germ cell development, neuronal differentiation, and survival (review by Lu and Zhou, 2007 [PubMed 17878917]).
Other Names:
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1, Rotamase Pin1, PIN1
Antigen Type:
Recombinant Protein
Gene Name: PIN1
Gene ID: 5300
NCBI Accession: NP_006212.1
Primary Accession: Q13526
Other Accession: BC002899
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Peptidyl-prolyl cis/trans isomerases (PPIases; EC 5.2.1.8), such as PIN1, catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. PIN1 is the only PPIase that specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. PIN1-catalyzed conformational regulation has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, germ cell development, neuronal differentiation, and survival (review by Lu and Zhou, 2007 [PubMed 17878917]).
Other Names:
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1, Rotamase Pin1, PIN1
Antigen Type:
Recombinant Protein
Gene Name: PIN1
Gene ID: 5300
NCBI Accession: NP_006212.1
Primary Accession: Q13526
Other Accession: BC002899
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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