PIN1 monoclonal, anti-human, mouse, rat, green monkey
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SKU
AC-AM2212B
Catalog Number: AC-AM2212B
Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 855CT1.7.5
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 855CT1.7.5
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.
Other Names:
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1, Rotamase Pin1, PIN1
Target/Specificity:
Purified His-tagged PIN1 protein was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: PIN1
Gene ID: 5300
Primary Accession: Q13526
NCBI Accession: NP_006212.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.
Other Names:
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1, Rotamase Pin1, PIN1
Target/Specificity:
Purified His-tagged PIN1 protein was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: PIN1
Gene ID: 5300
Primary Accession: Q13526
NCBI Accession: NP_006212.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
| Is Featured? | No |
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