Pin1 (phospho Ser16) Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES6594
Catalog Number: ELK-ES6594
Reactivity: Human, Mouse, Rat, Monkey
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
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Reactivity: Human, Mouse, Rat, Monkey
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
peptidylprolyl cis/trans isomerase, NIMA-interacting 1(PIN1) Homo sapiens Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011],
Alternative Names:
PIN1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1, Rotamase Pin1
Immunogen: The antiserum was produced against synthesized peptide derived from human Pin1 around the phosphorylation site of Ser16. AA range:1-50
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 18
GeneID: PIN1
Storage: -20°C/1 year
NOTE: For Research Use Only
peptidylprolyl cis/trans isomerase, NIMA-interacting 1(PIN1) Homo sapiens Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011],
Alternative Names:
PIN1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1, Rotamase Pin1
Immunogen: The antiserum was produced against synthesized peptide derived from human Pin1 around the phosphorylation site of Ser16. AA range:1-50
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 18
GeneID: PIN1
Storage: -20°C/1 year
NOTE: For Research Use Only
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