PINX1 Antibody (Center) Blocking Peptide

Background:
PINX1 (PIN2-interacting protein 1) is a ubiquitously expressed protein that localizes to nucleoli and telomere speckles. It contains a TID (telomerase inhibiting domain) domain which is capable of binding MCRS1, TERT and TERF1 and has been shown to be a potent telomerase inhibitor and putative tumor suppressor.

Other Names:
PIN2/TERF1-interacting telomerase inhibitor 1, Liver-related putative tumor suppressor, Pin2-interacting protein X1, Protein 67-11-3, TRF1-interacting protein 1, PINX1, LPTL, LPTS

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9227c was selected from the Center region of human PINX1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: PINX1

Gene ID: 54984
Primary Accession: Q96BK5
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.