PIP5K1B Polyclonal Antibody

Background:
Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking, and cytoskeletal organization. The PIPK family is divided into type I, type II and type III . Each type of the PIPK family phosphorylate distinct substrates and they contain an activation loop, which determines their enzymatic specificity and subcellular targeting . The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I , ∫, and , which are characterized by phosphorylating PI4P on the 5-hydroxyl . PIPK I (designated PIPK I ∫ in mouse) is expressed in brain tissue . PIPK I ∫, designated PIPK I a in mouse, is also called STM7. PIPK I has two variants produced by alternative splicing which are expressed in lung, brain, and kidneys.

Research Area: Signal Transduction

Synonyms:
MSS 4, MSS4, Phosphatidylinositol 4 phosphate 5 kinase type 1 beta, Phosphatidylinositol-4-phosphate 5-kinase type I beta, Phosphatidylinositol-4-phosphate 5-kinase type-1 beta, PI4P5K 1 beta, PI51B, PIP5K1-beta, PIP5K1B, PIP5KIbeta, Pipk 5 beta, Pipk 5b, Protein STM 7, Protein STM-7, PtdIns(4)P-5-kinase 1 beta, STM 7, STM7, STM7 LSB, Type I phosphatidylinositol 4 phosphate 5 kinase beta, Type I phosphatidylinositol-4-phosphate 5-kinase beta

Immunogen: Recombinant protein of human PIP5K1B

Swissprot: O14986
Gene Accession: BC030587

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-11779/sc-11778/sc-11777