PIP5K3 polyclonal, anti-human, mouse

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Carbohydrate Metabolism, Cell Motility, Signal Transduction

Description:
The 1-phosphatidylinositol-4-phosphate 5-kinase (PIP5K3) supports the intracellular PIP and PI 4,5-P(2) pools by generating PIP from PI and PI 4,5-P(2) from PI 4-P. PIP5K3 is involved in endosome-related membrane trafficking. Defects in PIP5K3 are the cause of corneal fleck dystrophy.

Alternate Names: FYVE finger-containing phosphoinositide kinase, 1-phosphatidylinositol-4-phosphate 5-kinase, Phosphatidylinositol-3-phosphate 5-kinase type III, PIP5K, PtdIns(4)P-5-kinase, PIKfyve, p235, PIP5K3

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500

Accession No.: Q9Y2I7, NP_055855

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PIP5K3.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.