PITRM1 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP12390c
Catalog Number: AC-AP12390c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31351
Applications: WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31351
Applications: WB
Datasheet
Request Information
Background:
ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.
Other Names:
Presequence protease, mitochondrial, hPreP, 3424-, Pitrilysin metalloproteinase 1, Metalloprotease 1, hMP1, PITRM1, KIAA1104, MP1
Target/Specificity:
This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1.
Antigen Region:
490-518
Antigen Type: Synthetic Peptide
Gene Name: PITRM1 (HGNC:17663)
Gene ID: 10531
Primary Accession: Q5JRX3
NCBI Accession: NP_001229236.1;NP_001229238.1;NP_055704.2
Other Accession: NP_055704.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.
Other Names:
Presequence protease, mitochondrial, hPreP, 3424-, Pitrilysin metalloproteinase 1, Metalloprotease 1, hMP1, PITRM1, KIAA1104, MP1
Target/Specificity:
This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1.
Antigen Region:
490-518
Antigen Type: Synthetic Peptide
Gene Name: PITRM1 (HGNC:17663)
Gene ID: 10531
Primary Accession: Q5JRX3
NCBI Accession: NP_001229236.1;NP_001229238.1;NP_055704.2
Other Accession: NP_055704.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review