PITX2 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP14021a
Catalog Number: AC-AP14021a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34027
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34027
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Other Names:
Pituitary homeobox 2, ALL1-responsive protein ARP1, Homeobox protein PITX2, Paired-like homeodomain transcription factor 2, RIEG bicoid-related homeobox transcription factor, Solurshin, PITX2, ARP1, RGS, RIEG, RIEG1
Target/Specificity:
This PITX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human PITX2.
Antigen Region:
42-71
Antigen Type: Synthetic Peptide
Gene Name: PITX2 (HGNC:9005)
Gene ID: 5308
Primary Accession: Q99697
NCBI Accession: NP_000316.2;NP_001191326.1;NP_001191327.1;NP_001191328.1;NP_700475.1;NP_700476.1
Other Accession: NP_700476.1;NP_700475.1;NP_000316.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Other Names:
Pituitary homeobox 2, ALL1-responsive protein ARP1, Homeobox protein PITX2, Paired-like homeodomain transcription factor 2, RIEG bicoid-related homeobox transcription factor, Solurshin, PITX2, ARP1, RGS, RIEG, RIEG1
Target/Specificity:
This PITX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human PITX2.
Antigen Region:
42-71
Antigen Type: Synthetic Peptide
Gene Name: PITX2 (HGNC:9005)
Gene ID: 5308
Primary Accession: Q99697
NCBI Accession: NP_000316.2;NP_001191326.1;NP_001191327.1;NP_001191328.1;NP_700475.1;NP_700476.1
Other Accession: NP_700476.1;NP_700475.1;NP_000316.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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